Marazine
Brand names,
Marazine
Analogs
Marazine
Brand Names Mixture
Marazine
Chemical_Formula
C18H22N2
Marazine
RX_link
No information avaliable
Marazine
fda sheet
Marazine
msds (material safety sheet)
Marazine
Synthesis Reference
No information avaliable
Marazine
Molecular Weight
266.381 g/mol
Marazine
Melting Point
No information avaliable
Marazine
H2O Solubility
No information avaliable
Marazine
State
Solid
Marazine
LogP
3.338
Marazine
Dosage Forms
Liquid
Marazine
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
Marazine
Pharmacology
Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Marazine
Absorption
No information avaliable
Marazine
side effects and Toxicity
No information avaliable
Marazine
Patient Information
No information avaliable
Marazine
Organisms Affected
Humans and other mammals