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Doxapram Brand names, Doxapram Analogs

Doxapram Brand Names Mixture

  • No information avaliable

Doxapram Chemical_Formula


Doxapram RX_link

Doxapram fda sheet

Doxapram FDA

Doxapram msds (material safety sheet)

Doxapram MSDS

Doxapram Synthesis Reference

No information avaliable

Doxapram Molecular Weight

378.507 g/mol

Doxapram Melting Point

No information avaliable

Doxapram H2O Solubility

Sparingly soluble

Doxapram State


Doxapram LogP


Doxapram Dosage Forms

Liquid; Solution

Doxapram Indication

For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.

Doxapram Pharmacology

Doxapram is an analeptic agent (a stimulant of the central nervous system). The respiratory stimulant action is manifested by an increase in tidal volume associated with a slight increase in respiratory rate. A pressor response may result following doxapram administration. Provided there is no impairment of cardiac function, the pressor effect is more marked in hypovolemic than in normovolemic states. The pressor response is due to the improved cardiac output rather than peripheral vasoconstriction. Following doxapram administration, an increased release of catecholamines has been noted.

Doxapram Absorption

No information avaliable

Doxapram side effects and Toxicity

Intravenous LD50 values in the mouse and rat were approximately 75 mg/kg and in the cat and dog were 40 to 80 mg/kg. Symptoms of overdosage are extensions of the pharmacologic effects of the drug. Excessive pressor effect, tachycardia, skeletal muscle hyperactivity, and enhanced deep tendon reflexes may be early signs of overdosage.

Doxapram Patient Information

No information avaliable

Doxapram Organisms Affected

Humans and other mammals