PharmacyCodes



Doxapram HCL en es it fr

Doxapram HCL Brand names, Doxapram HCL Analogs

Doxapram HCL Brand Names Mixture

  • No information avaliable

Doxapram HCL Chemical_Formula

C24H30N2O2

Doxapram HCL RX_link

http://www.rxlist.com/cgi/generic2/doxapram.htm

Doxapram HCL fda sheet

Doxapram_HCL FDA

Doxapram HCL msds (material safety sheet)

Doxapram_HCL MSDS

Doxapram HCL Synthesis Reference

No information avaliable

Doxapram HCL Molecular Weight

378.507 g/mol

Doxapram HCL Melting Point

No information avaliable

Doxapram HCL H2O Solubility

Sparingly soluble

Doxapram HCL State

Solid

Doxapram HCL LogP

3.938

Doxapram HCL Dosage Forms

Liquid; Solution

Doxapram HCL Indication

For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.

Doxapram HCL Pharmacology

Doxapram is an analeptic agent (a stimulant of the central nervous system). The respiratory stimulant action is manifested by an increase in tidal volume associated with a slight increase in respiratory rate. A pressor response may result following doxapram administration. Provided there is no impairment of cardiac function, the pressor effect is more marked in hypovolemic than in normovolemic states. The pressor response is due to the improved cardiac output rather than peripheral vasoconstriction. Following doxapram administration, an increased release of catecholamines has been noted.

Doxapram HCL Absorption

No information avaliable

Doxapram HCL side effects and Toxicity

Intravenous LD50 values in the mouse and rat were approximately 75 mg/kg and in the cat and dog were 40 to 80 mg/kg. Symptoms of overdosage are extensions of the pharmacologic effects of the drug. Excessive pressor effect, tachycardia, skeletal muscle hyperactivity, and enhanced deep tendon reflexes may be early signs of overdosage.

Doxapram HCL Patient Information

No information avaliable

Doxapram HCL Organisms Affected

Humans and other mammals