Cyclizine
Brand names,
Cyclizine
Analogs
Cyclizine
Brand Names Mixture
Cyclizine
Chemical_Formula
C18H22N2
Cyclizine
RX_link
No information avaliable
Cyclizine
fda sheet
Cyclizine
msds (material safety sheet)
Cyclizine
Synthesis Reference
No information avaliable
Cyclizine
Molecular Weight
266.381 g/mol
Cyclizine
Melting Point
No information avaliable
Cyclizine
H2O Solubility
No information avaliable
Cyclizine
State
Solid
Cyclizine
LogP
3.338
Cyclizine
Dosage Forms
Liquid
Cyclizine
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
Cyclizine
Pharmacology
Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Cyclizine
Absorption
No information avaliable
Cyclizine
side effects and Toxicity
No information avaliable
Cyclizine
Patient Information
No information avaliable
Cyclizine
Organisms Affected
Humans and other mammals