Capreomycin sulphate
Brand names,
Capreomycin sulphate
Analogs
Capreomycin sulphate
Brand Names Mixture
Capreomycin sulphate
Chemical_Formula
C25H46N14O12S
Capreomycin sulphate
RX_link
No information avaliable
Capreomycin sulphate
fda sheet
Capreomycin sulphate
msds (material safety sheet)
Capreomycin sulphate
Synthesis Reference
No information avaliable
Capreomycin sulphate
Molecular Weight
766.786 g/mol
Capreomycin sulphate
Melting Point
No information avaliable
Capreomycin sulphate
H2O Solubility
Soluble in water as disulfate salt.
Capreomycin sulphate
State
Solid
Capreomycin sulphate
LogP
-9.609
Capreomycin sulphate
Dosage Forms
Capsule; Cream; Liquid; Ointment; Powder for solution; Solution; Suspension; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Capreomycin sulphate
Indication
Used in the treatment of tuberculosis in combination with other drugs.
Capreomycin sulphate
Pharmacology
Capreomycin is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety of bacteria, including bacteria responsible for causing tuberculosis (TB).
Capreomycin sulphate
Absorption
Not absorbed in significant quantities from the gastrointestinal tract and must be administered parenterally.
Capreomycin sulphate
side effects and Toxicity
Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter's syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD50) in mice was 514 mg/kg.
Capreomycin sulphate
Patient Information
Capreomycin sulphate
Organisms Affected
Enteric bacteria and other eubacteria