Capastat sulfate
Brand names,
Capastat sulfate
Analogs
Capastat sulfate
Brand Names Mixture
Capastat sulfate
Chemical_Formula
C25H46N14O12S
Capastat sulfate
RX_link
No information avaliable
Capastat sulfate
fda sheet
Capastat sulfate
msds (material safety sheet)
Capastat sulfate
Synthesis Reference
No information avaliable
Capastat sulfate
Molecular Weight
766.786 g/mol
Capastat sulfate
Melting Point
No information avaliable
Capastat sulfate
H2O Solubility
Soluble in water as disulfate salt.
Capastat sulfate
State
Solid
Capastat sulfate
LogP
-9.609
Capastat sulfate
Dosage Forms
Capsule; Cream; Liquid; Ointment; Powder for solution; Solution; Suspension; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Capastat sulfate
Indication
Used in the treatment of tuberculosis in combination with other drugs.
Capastat sulfate
Pharmacology
Capreomycin is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety of bacteria, including bacteria responsible for causing tuberculosis (TB).
Capastat sulfate
Absorption
Not absorbed in significant quantities from the gastrointestinal tract and must be administered parenterally.
Capastat sulfate
side effects and Toxicity
Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter's syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD50) in mice was 514 mg/kg.
Capastat sulfate
Patient Information
Capastat sulfate
Organisms Affected
Enteric bacteria and other eubacteria