Capreomycin
Brand names,
Capreomycin
Analogs
Capreomycin
Brand Names Mixture
Capreomycin
Chemical_Formula
C25H46N14O12S
Capreomycin
RX_link
No information avaliable
Capreomycin
fda sheet
Capreomycin
msds (material safety sheet)
Capreomycin
Synthesis Reference
No information avaliable
Capreomycin
Molecular Weight
766.786 g/mol
Capreomycin
Melting Point
No information avaliable
Capreomycin
H2O Solubility
Soluble in water as disulfate salt.
Capreomycin
State
Solid
Capreomycin
LogP
-9.609
Capreomycin
Dosage Forms
Capsule; Cream; Liquid; Ointment; Powder for solution; Solution; Suspension; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Capreomycin
Indication
Used in the treatment of tuberculosis in combination with other drugs.
Capreomycin
Pharmacology
Capreomycin is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety of bacteria, including bacteria responsible for causing tuberculosis (TB).
Capreomycin
Absorption
Not absorbed in significant quantities from the gastrointestinal tract and must be administered parenterally.
Capreomycin
side effects and Toxicity
Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter's syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD50) in mice was 514 mg/kg.
Capreomycin
Patient Information
Capreomycin
Organisms Affected
Enteric bacteria and other eubacteria