Capastat
Brand names,
Capastat
Analogs
Capastat
Brand Names Mixture
Capastat
Chemical_Formula
C25H46N14O12S
Capastat
RX_link
No information avaliable
Capastat
fda sheet
Capastat
msds (material safety sheet)
Capastat
Synthesis Reference
No information avaliable
Capastat
Molecular Weight
766.786 g/mol
Capastat
Melting Point
No information avaliable
Capastat
H2O Solubility
Soluble in water as disulfate salt.
Capastat
State
Solid
Capastat
LogP
-9.609
Capastat
Dosage Forms
Capsule; Cream; Liquid; Ointment; Powder for solution; Solution; Suspension; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Capastat
Indication
Used in the treatment of tuberculosis in combination with other drugs.
Capastat
Pharmacology
Capreomycin is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety of bacteria, including bacteria responsible for causing tuberculosis (TB).
Capastat
Absorption
Not absorbed in significant quantities from the gastrointestinal tract and must be administered parenterally.
Capastat
side effects and Toxicity
Hypokalemia, hypocalcemia, hypomagnesemia, and an electrolyte disturbance resembling Bartter's syndrome have been reported to occur in patients with capreomycin toxicity. The subcutaneous median lethal dose (LD50) in mice was 514 mg/kg.
Capastat
Patient Information
Capastat
Organisms Affected
Enteric bacteria and other eubacteria