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Black Leaf 40 Brand names, Black Leaf 40 Analogs

Black Leaf 40 Brand Names Mixture

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Black Leaf 40 Chemical_Formula


Black Leaf 40 RX_link

Black Leaf 40 fda sheet

Black_Leaf_40 FDA

Black Leaf 40 msds (material safety sheet)

Black_Leaf_40 MSDS

Black Leaf 40 Synthesis Reference

Pinner, Ber. 26, 294 (1893)

Black Leaf 40 Molecular Weight

162.232 g/mol

Black Leaf 40 Melting Point

-79 oC

Black Leaf 40 H2O Solubility

1 g/mL

Black Leaf 40 State


Black Leaf 40 LogP


Black Leaf 40 Dosage Forms

Gum; Inhaler; Patch

Black Leaf 40 Indication

For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.

Black Leaf 40 Pharmacology

Nicotine, the primary alkaloid in tobacco products binds stereo-selectively to nicotinic-cholinergic receptors on autonomic ganglia, the adrenal medulla, neuromuscular junctions and in the brain. Nicotine exerts two effects, a stimulant effect exerted at the locus ceruleus and a reward effect in the limbic system. Itranvenous administration of nicotine causes release of acetylcholine, norepinephrine, dopamine, serotonine, vasopressin, beta-endorphin and ACTH. Nicotine is a highly addictive substance. Nicotine also induces peripheral vasoconstriction, tachycardia and elevated blood pressure. Nicotine inhalers and patches are used to treat smoking withdrawl syndrome. Nicotine is classified as a stimulant of autonomic ganglia.

Black Leaf 40 Absorption

Absorption of nicotine through the buccal mucosa is relatively slow and the high and rapid rise followed by the decline in nicotine arterial plasma concentrations seen with cigarette smoking are not achieved with the inhaler. About 10% of absorbed nicotine is excreted unchanged in urine.

Black Leaf 40 side effects and Toxicity

Symptoms of overdose include nausea, abdominal pain, vomiting, diarrhea, diaphoresis, flushing, dizziness, disturbed hearing and vision, confusion, weakness, palpitations, altered respiration and hypotension. LD50= 24 mg/kg (orally in mice).

Black Leaf 40 Patient Information

A patient information sheet is included in the package of NICOTROL Inhaler cartridges dispensed to the patient. Patients should be encouraged to read the information sheet carefully and to ask their physician and pharmacist about the proper use of the product .

Patients must be advised to keep both used and unused cartridges out of the reach of children and pets.

Black Leaf 40 Organisms Affected

Humans and other mammals