Azithromycin

Azithromycin Brand names, Azithromycin Analogs

Azithromycin Brand Names Mixture

No information avaliable

Azithromycin Chemical_Formula

C₃₈H₇₂N₂O₁₂

Azithromycin RX_link

http://www.rxlist.com/cgi/generic/azith.htm

Azithromycin fda sheet

Azithromycin FDA

Azithromycin msds (material safety sheet)

Azithromycin MSDS

Azithromycin Synthesis Reference

G.Kobrehel, S.Djokic, U.S. pat. 4,517,359 (1982, 1985 to Sour Pliva)

Azithromycin Molecular Weight

748.985 g/mol

Azithromycin Melting Point

113-115 ^oC

Azithromycin H₂O Solubility

slight

Azithromycin State

Solid

Azithromycin LogP

2.461

Azithromycin Dosage Forms

Oral suspension; Capsule; Tablet; Powder for solution

Azithromycin Indication

For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions: H. influenzae, M. catarrhalis, S. pneumoniae, C. pneumoniae, M. pneumoniae, S. pyogenes, S. aureus, S. agal

Azithromycin Pharmacology

Azithromycin, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action.

Azithromycin Absorption

37% (oral administration)

Azithromycin side effects and Toxicity

Potentially serious side effects of angioedema and cholestatic jaundice were reported

Azithromycin Patient Information

Patients should be instructed to take Zmax on an empty stomach (at least 1 hour before or 2 hours following a meal).

Patients should be instructed to immediately contact a physician if any signs of an allergic reaction occur.

Patients who vomit within the first hour should contact their health care provider about further treatment.

Keep bottle tightly closed. Store at room temperature. Use within 12 hours of constitution. Shake bottle well before use. The entire contents of the bottle should be consumed.

Patients should be advised that Zmax may be taken without regard to antacids containing magnesium hydroxide and/or aluminum hydroxide.

Patients should be counseled that antibacterial drugs including Zmax should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). Not taking the complete prescribed dose may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Zmax or other antibacterial drugs in the future.

Azithromycin Organisms Affected

Enteric bacteria and other eubacteria