Azithramycine

Azithramycine Brand names, Azithramycine Analogs

Azithramycine Brand Names Mixture

No information avaliable

Azithramycine Chemical_Formula

C₃₈H₇₂N₂O₁₂

Azithramycine RX_link

http://www.rxlist.com/cgi/generic/azith.htm

Azithramycine fda sheet

Azithramycine FDA

Azithramycine msds (material safety sheet)

Azithramycine MSDS

Azithramycine Synthesis Reference

G.Kobrehel, S.Djokic, U.S. pat. 4,517,359 (1982, 1985 to Sour Pliva)

Azithramycine Molecular Weight

748.985 g/mol

Azithramycine Melting Point

113-115 ^oC

Azithramycine H₂O Solubility

slight

Azithramycine State

Solid

Azithramycine LogP

2.461

Azithramycine Dosage Forms

Oral suspension; Capsule; Tablet; Powder for solution

Azithramycine Indication

For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions: H. influenzae, M. catarrhalis, S. pneumoniae, C. pneumoniae, M. pneumoniae, S. pyogenes, S. aureus, S. agal

Azithramycine Pharmacology

Azithromycin, a semisynthetic antibiotic belonging to the macrolide subgroup of azalides, is used to treat STDs due to chlamydia and gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis, and Mycobacterium avium complex (MAC) in patients with advanced HIV disease. Similar in structure to erythromycin. azithromycin reaches higher intracellular concentrations than erythromycin, increasing its efficacy and duration of action.

Azithramycine Absorption

37% (oral administration)

Azithramycine side effects and Toxicity

Potentially serious side effects of angioedema and cholestatic jaundice were reported

Azithramycine Patient Information

Patients should be instructed to take Zmax on an empty stomach (at least 1 hour before or 2 hours following a meal).

Patients should be instructed to immediately contact a physician if any signs of an allergic reaction occur.

Patients who vomit within the first hour should contact their health care provider about further treatment.

Keep bottle tightly closed. Store at room temperature. Use within 12 hours of constitution. Shake bottle well before use. The entire contents of the bottle should be consumed.

Patients should be advised that Zmax may be taken without regard to antacids containing magnesium hydroxide and/or aluminum hydroxide.

Patients should be counseled that antibacterial drugs including Zmax should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). Not taking the complete prescribed dose may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Zmax or other antibacterial drugs in the future.

Azithramycine Organisms Affected

Enteric bacteria and other eubacteria