Apomorphinium Chloride Hemihydrate
Brand names,
Apomorphinium Chloride Hemihydrate
Analogs
Apomorphinium Chloride Hemihydrate
Brand Names Mixture
- Homeopathic Remedy Thc No. 48 Dps (Antimony Trisulfide + Apomorphine + Ipecac + Phosphorus + Pulsatilla)
Apomorphinium Chloride Hemihydrate
Chemical_Formula
C17H17NO2
Apomorphinium Chloride Hemihydrate
RX_link
http://www.rxlist.com/cgi/generic3/apokyn.htm
Apomorphinium Chloride Hemihydrate
fda sheet
Apomorphinium Chloride Hemihydrate
msds (material safety sheet)
Apomorphinium Chloride Hemihydrate
Synthesis Reference
J. L. Neumeyer et al., J. Pharm. Sci. 59, 1850 (1970);
Apomorphinium Chloride Hemihydrate
Molecular Weight
267.322 g/mol
Apomorphinium Chloride Hemihydrate
Melting Point
No information avaliable
Apomorphinium Chloride Hemihydrate
H2O Solubility
1.66E+004 mg/L
Apomorphinium Chloride Hemihydrate
State
Solid
Apomorphinium Chloride Hemihydrate
LogP
3.03
Apomorphinium Chloride Hemihydrate
Dosage Forms
Subcutaneous solution (not for IV)
Apomorphinium Chloride Hemihydrate
Indication
For the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
Apomorphinium Chloride Hemihydrate
Pharmacology
Apomorphine is a type of dopaminergic agonist, a morphine derivative which primarily affects the hypothalamic region of the brain. Drugs containing this substance are sometimes used in the treatment of Parkinson's disease or erectile dysfunction. In higher doses it is a highly effective emetic.
Apomorphinium Chloride Hemihydrate
Absorption
100% following subcutaneous administration
Apomorphinium Chloride Hemihydrate
side effects and Toxicity
LD50=0.6 mmoles/kg (mice, intraperitoneal)
Apomorphinium Chloride Hemihydrate
Patient Information
Apomorphinium Chloride Hemihydrate
Organisms Affected
Humans and other mammals