Anistreplase
Brand names,
Anistreplase
Analogs
Anistreplase
Brand Names Mixture
- Synotic Otic Solution (Dimethyl sulfoxide + Fluocinolone acetonide)
Anistreplase
Chemical_Formula
C2569H3928N746O781S40
Anistreplase
RX_link
No information avaliable
Anistreplase
fda sheet
Anistreplase
msds (material safety sheet)
Anistreplase
Synthesis Reference
No information avaliable
Anistreplase
Molecular Weight
59042.3
Anistreplase
Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
Anistreplase
H2O Solubility
No information avaliable
Anistreplase
State
Liquid
Anistreplase
LogP
-0.516
Anistreplase
Dosage Forms
Powder for solution
Anistreplase
Indication
For lysis of acute pulmonary emboli, intracoronary emboli and management of myocardial infarction
Anistreplase
Pharmacology
Anistreplase cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action. This helps eliminate blood clots or arterial blockages that cause myocardial infarction.
Anistreplase
Absorption
No information avaliable
Anistreplase
side effects and Toxicity
No information avaliable
Anistreplase
Patient Information
No information avaliable
Anistreplase
Organisms Affected
Humans and other mammals