Ametik hydrochloride
Ametik hydrochloride Brand names, Ametik hydrochloride Analogs
Ametik hydrochloride Brand Names Mixture
- Alphasel tablets (calcium phosphate [dibasic] + cobalt sulfate + D-alpha tocopheryl acetate + selenium sulfide)
- Previte (neomycin sulfate + selenium sulfide + streptomycin sulfate + vitamin A + vitamin D + vitamin E + vitamin K1)
Ametik hydrochloride Chemical_Formula
C14H12N6O
Ametik hydrochloride RX_link
No information avaliable
Ametik hydrochloride fda sheet
Ametik hydrochloride msds (material safety sheet)
Ametik hydrochloride Synthesis Reference
No information avaliable
Ametik hydrochloride Molecular Weight
280.285 g/mol
Ametik hydrochloride Melting Point
No information avaliable
Ametik hydrochloride H2O Solubility
No information avaliable
Ametik hydrochloride State
Solid
Ametik hydrochloride LogP
2.759
Ametik hydrochloride Dosage Forms
Intravenous (loading dose of 12 to 24 micrograms/kg over 10 minutes followed by a continuous infusion of 0.05 to 0.2 micrograms/kg per minute, adjusted according to response)
Ametik hydrochloride Indication
For short term treatment of acutely decompensated severe chronic heart failure (CHF).
Ametik hydrochloride Pharmacology
Levosimendan is a new Ca2+-sensitizing inotropic agent. Ca2+ sensitizers represent a new class of inotropic agents, which overcome the disadvantages associated with currently available inotropic agents in as they are not associated with an increased risk of arrhythmias, cell injury and death due to Ca2+ overload in myocardial cells; they do not increase the activation energy; and they have the potential to reverse contractile dysfunction under pathophysiologic conditions, such as acidosis or myocardial stunning. Levosimendan has not been approved for use in the U.S. or Canada.
Ametik hydrochloride Absorption
The bioavailability of oral levosimendan is 85 ± 6% in healthy volunteers and 84 ± 4% in patients.
Ametik hydrochloride side effects and Toxicity
No information avaliable
Ametik hydrochloride Patient Information
No information avaliable
Ametik hydrochloride Organisms Affected
Humans and other mammals
