Nauseton
Brand names,
Nauseton
Analogs
Nauseton
Brand Names Mixture
- Alphasel tablets (calcium phosphate [dibasic] + cobalt sulfate + D-alpha tocopheryl acetate + selenium sulfide)
- Previte (neomycin sulfate + selenium sulfide + streptomycin sulfate + vitamin A + vitamin D + vitamin E + vitamin K1)
Nauseton
Chemical_Formula
C14H12N6O
Nauseton
RX_link
No information avaliable
Nauseton
fda sheet
Nauseton
msds (material safety sheet)
Nauseton
Synthesis Reference
No information avaliable
Nauseton
Molecular Weight
280.285 g/mol
Nauseton
Melting Point
No information avaliable
Nauseton
H2O Solubility
No information avaliable
Nauseton
State
Solid
Nauseton
LogP
2.759
Nauseton
Dosage Forms
Intravenous (loading dose of 12 to 24 micrograms/kg over 10 minutes followed by a continuous infusion of 0.05 to 0.2 micrograms/kg per minute, adjusted according to response)
Nauseton
Indication
For short term treatment of acutely decompensated severe chronic heart failure (CHF).
Nauseton
Pharmacology
Levosimendan is a new Ca2+-sensitizing inotropic agent. Ca2+ sensitizers represent a new class of inotropic agents, which overcome the disadvantages associated with currently available inotropic agents in as they are not associated with an increased risk of arrhythmias, cell injury and death due to Ca2+ overload in myocardial cells; they do not increase the activation energy; and they have the potential to reverse contractile dysfunction under pathophysiologic conditions, such as acidosis or myocardial stunning. Levosimendan has not been approved for use in the U.S. or Canada.
Nauseton
Absorption
The bioavailability of oral levosimendan is 85 ± 6% in healthy volunteers and 84 ± 4% in patients.
Nauseton
side effects and Toxicity
No information avaliable
Nauseton
Patient Information
No information avaliable
Nauseton
Organisms Affected
Humans and other mammals