Benzacot
Brand names,
Benzacot
Analogs
Benzacot
Brand Names Mixture
- Alphasel tablets (calcium phosphate [dibasic] + cobalt sulfate + D-alpha tocopheryl acetate + selenium sulfide)
- Previte (neomycin sulfate + selenium sulfide + streptomycin sulfate + vitamin A + vitamin D + vitamin E + vitamin K1)
Benzacot
Chemical_Formula
C14H12N6O
Benzacot
RX_link
No information avaliable
Benzacot
fda sheet
Benzacot
msds (material safety sheet)
Benzacot
Synthesis Reference
No information avaliable
Benzacot
Molecular Weight
280.285 g/mol
Benzacot
Melting Point
No information avaliable
Benzacot
H2O Solubility
No information avaliable
Benzacot
State
Solid
Benzacot
LogP
2.759
Benzacot
Dosage Forms
Intravenous (loading dose of 12 to 24 micrograms/kg over 10 minutes followed by a continuous infusion of 0.05 to 0.2 micrograms/kg per minute, adjusted according to response)
Benzacot
Indication
For short term treatment of acutely decompensated severe chronic heart failure (CHF).
Benzacot
Pharmacology
Levosimendan is a new Ca2+-sensitizing inotropic agent. Ca2+ sensitizers represent a new class of inotropic agents, which overcome the disadvantages associated with currently available inotropic agents in as they are not associated with an increased risk of arrhythmias, cell injury and death due to Ca2+ overload in myocardial cells; they do not increase the activation energy; and they have the potential to reverse contractile dysfunction under pathophysiologic conditions, such as acidosis or myocardial stunning. Levosimendan has not been approved for use in the U.S. or Canada.
Benzacot
Absorption
The bioavailability of oral levosimendan is 85 ± 6% in healthy volunteers and 84 ± 4% in patients.
Benzacot
side effects and Toxicity
No information avaliable
Benzacot
Patient Information
No information avaliable
Benzacot
Organisms Affected
Humans and other mammals