PharmacyCodes



Trimethobenzamidum [INN-Latin] en es it fr

Trimethobenzamidum [INN-Latin] Brand names, Trimethobenzamidum [INN-Latin] Analogs

Trimethobenzamidum [INN-Latin] Brand Names Mixture

  • Alphasel tablets (calcium phosphate [dibasic] + cobalt sulfate + D-alpha tocopheryl acetate + selenium sulfide)
  • Previte (neomycin sulfate + selenium sulfide + streptomycin sulfate + vitamin A + vitamin D + vitamin E + vitamin K1)

Trimethobenzamidum [INN-Latin] Chemical_Formula

C14H12N6O

Trimethobenzamidum [INN-Latin] RX_link

No information avaliable

Trimethobenzamidum [INN-Latin] fda sheet

Trimethobenzamidum [INN-Latin] msds (material safety sheet)

Trimethobenzamidum_[INN-Latin] MSDS

Trimethobenzamidum [INN-Latin] Synthesis Reference

No information avaliable

Trimethobenzamidum [INN-Latin] Molecular Weight

280.285 g/mol

Trimethobenzamidum [INN-Latin] Melting Point

No information avaliable

Trimethobenzamidum [INN-Latin] H2O Solubility

No information avaliable

Trimethobenzamidum [INN-Latin] State

Solid

Trimethobenzamidum [INN-Latin] LogP

2.759

Trimethobenzamidum [INN-Latin] Dosage Forms

Intravenous (loading dose of 12 to 24 micrograms/kg over 10 minutes followed by a continuous infusion of 0.05 to 0.2 micrograms/kg per minute, adjusted according to response)

Trimethobenzamidum [INN-Latin] Indication

For short term treatment of acutely decompensated severe chronic heart failure (CHF).

Trimethobenzamidum [INN-Latin] Pharmacology

Levosimendan is a new Ca2+-sensitizing inotropic agent. Ca2+ sensitizers represent a new class of inotropic agents, which overcome the disadvantages associated with currently available inotropic agents in as they are not associated with an increased risk of arrhythmias, cell injury and death due to Ca2+ overload in myocardial cells; they do not increase the activation energy; and they have the potential to reverse contractile dysfunction under pathophysiologic conditions, such as acidosis or myocardial stunning. Levosimendan has not been approved for use in the U.S. or Canada.

Trimethobenzamidum [INN-Latin] Absorption

The bioavailability of oral levosimendan is 85 ± 6% in healthy volunteers and 84 ± 4% in patients.

Trimethobenzamidum [INN-Latin] side effects and Toxicity

No information avaliable

Trimethobenzamidum [INN-Latin] Patient Information

No information avaliable

Trimethobenzamidum [INN-Latin] Organisms Affected

Humans and other mammals