Activase (Genentech Inc)
Brand names,
Activase (Genentech Inc)
Analogs
Activase (Genentech Inc)
Brand Names Mixture
Activase (Genentech Inc)
Chemical_Formula
C2569H3928N746O781S40
Activase (Genentech Inc)
RX_link
http://www.rxlist.com/cgi/generic/alteplas.htm
Activase (Genentech Inc)
fda sheet
Activase (Genentech Inc)
msds (material safety sheet)
Activase (Genentech Inc)
Synthesis Reference
No information avaliable
Activase (Genentech Inc)
Molecular Weight
59042.3
Activase (Genentech Inc)
Melting Point
60 oC (Novokhatny, V.V. et al., J. Biol. Chem. 266:12994-123002 (1991))
Activase (Genentech Inc)
H2O Solubility
No information avaliable
Activase (Genentech Inc)
State
Liquid
Activase (Genentech Inc)
LogP
-0.516
Activase (Genentech Inc)
Dosage Forms
Powder for solution
Activase (Genentech Inc)
Indication
For management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli
Activase (Genentech Inc)
Pharmacology
Activase binds to fibrin in a thrombus and converts the entrapped plasminogen to plasmin. It also produces limited conversion of plasminogen in the absence of fibrin.
Activase (Genentech Inc)
Absorption
No information avaliable
Activase (Genentech Inc)
side effects and Toxicity
No information avaliable
Activase (Genentech Inc)
Patient Information
BIOD00050.html
Activase (Genentech Inc)
Organisms Affected
Humans and other mammals