Ethyl Tuads Rodform en es it fr

Ethyl Tuads Rodform Brand names, Ethyl Tuads Rodform Analogs

Ethyl Tuads Rodform Brand Names Mixture

  • No information avaliable

Ethyl Tuads Rodform Chemical_Formula

C10H20N2S4

Ethyl Tuads Rodform RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Ethyl Tuads Rodform fda sheet

Ethyl Tuads Rodform msds (material safety sheet)

Ethyl_Tuads_Rodform MSDS

Ethyl Tuads Rodform Synthesis Reference

No information avaliable

Ethyl Tuads Rodform Molecular Weight

296.543 g/mol

Ethyl Tuads Rodform Melting Point

71.5 oC

Ethyl Tuads Rodform H2O Solubility

4.09 mg/L

Ethyl Tuads Rodform State

Solid

Ethyl Tuads Rodform LogP

4.422

Ethyl Tuads Rodform Dosage Forms

Tablet

Ethyl Tuads Rodform Indication

For the treatment and management of chronic alcoholism

Ethyl Tuads Rodform Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Ethyl Tuads Rodform Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Ethyl Tuads Rodform side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Ethyl Tuads Rodform Patient Information

No information avaliable

Ethyl Tuads Rodform Organisms Affected

Humans and other mammals