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Anteyl Brand names, Anteyl Analogs

Anteyl Brand Names Mixture

  • No information avaliable

Anteyl Chemical_Formula

C10H20N2S4

Anteyl RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Anteyl fda sheet

Anteyl msds (material safety sheet)

Anteyl MSDS

Anteyl Synthesis Reference

No information avaliable

Anteyl Molecular Weight

296.543 g/mol

Anteyl Melting Point

71.5 oC

Anteyl H2O Solubility

4.09 mg/L

Anteyl State

Solid

Anteyl LogP

4.422

Anteyl Dosage Forms

Tablet

Anteyl Indication

For the treatment and management of chronic alcoholism

Anteyl Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Anteyl Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Anteyl side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Anteyl Patient Information

No information avaliable

Anteyl Organisms Affected

Humans and other mammals