Sanceler Tet en es it fr

Sanceler Tet Brand names, Sanceler Tet Analogs

Sanceler Tet Brand Names Mixture

  • No information avaliable

Sanceler Tet Chemical_Formula

C10H20N2S4

Sanceler Tet RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Sanceler Tet fda sheet

Sanceler Tet msds (material safety sheet)

Sanceler_Tet MSDS

Sanceler Tet Synthesis Reference

No information avaliable

Sanceler Tet Molecular Weight

296.543 g/mol

Sanceler Tet Melting Point

71.5 oC

Sanceler Tet H2O Solubility

4.09 mg/L

Sanceler Tet State

Solid

Sanceler Tet LogP

4.422

Sanceler Tet Dosage Forms

Tablet

Sanceler Tet Indication

For the treatment and management of chronic alcoholism

Sanceler Tet Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Sanceler Tet Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Sanceler Tet side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Sanceler Tet Patient Information

No information avaliable

Sanceler Tet Organisms Affected

Humans and other mammals