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Anti-Ethyl Brand names, Anti-Ethyl Analogs

Anti-Ethyl Brand Names Mixture

  • No information avaliable

Anti-Ethyl Chemical_Formula

C10H20N2S4

Anti-Ethyl RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Anti-Ethyl fda sheet

Anti-Ethyl msds (material safety sheet)

Anti-Ethyl MSDS

Anti-Ethyl Synthesis Reference

No information avaliable

Anti-Ethyl Molecular Weight

296.543 g/mol

Anti-Ethyl Melting Point

71.5 oC

Anti-Ethyl H2O Solubility

4.09 mg/L

Anti-Ethyl State

Solid

Anti-Ethyl LogP

4.422

Anti-Ethyl Dosage Forms

Tablet

Anti-Ethyl Indication

For the treatment and management of chronic alcoholism

Anti-Ethyl Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Anti-Ethyl Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Anti-Ethyl side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Anti-Ethyl Patient Information

No information avaliable

Anti-Ethyl Organisms Affected

Humans and other mammals