p-Hydroxyphenyl benzyl ether
Brand names,
p-Hydroxyphenyl benzyl ether
Analogs
p-Hydroxyphenyl benzyl ether
Brand Names Mixture
p-Hydroxyphenyl benzyl ether
Chemical_Formula
C21H22N2O5S
p-Hydroxyphenyl benzyl ether
RX_link
http://www.rxlist.com/cgi/generic3/nafcillin.htm
p-Hydroxyphenyl benzyl ether
fda sheet
p-Hydroxyphenyl benzyl ether
msds (material safety sheet)
p-Hydroxyphenyl benzyl ether
Synthesis Reference
No information avaliable
p-Hydroxyphenyl benzyl ether
Molecular Weight
414.476 g/mol
p-Hydroxyphenyl benzyl ether
Melting Point
No information avaliable
p-Hydroxyphenyl benzyl ether
H2O Solubility
Soluble
p-Hydroxyphenyl benzyl ether
State
Solid
p-Hydroxyphenyl benzyl ether
LogP
3.373
p-Hydroxyphenyl benzyl ether
Dosage Forms
Powder for solution
p-Hydroxyphenyl benzyl ether
Indication
For the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drugs.
p-Hydroxyphenyl benzyl ether
Pharmacology
Nafcillin is a semisynthetic antibiotic substance derived from 6-amino-penicillanic acid. The drugs in this class are highly resistant to inactivation by staphylococcal penicillinase and are active against penicillinase-producing and non penicillinase-producing strains of Staphylococcus aureus. The penicillinase- resistant penicillins are active in vitro against a variety of other bacteria.
p-Hydroxyphenyl benzyl ether
Absorption
No information avaliable
p-Hydroxyphenyl benzyl ether
side effects and Toxicity
Serious toxicity is unlikely following large doses of nafcillin. Acute ingestion of large doses of nafcillin may cause nausea, vomiting, diarrhea and abdominal pain. Acute oliguric renal failure and hematuria may occur following large doses.
p-Hydroxyphenyl benzyl ether
Patient Information
p-Hydroxyphenyl benzyl ether
Organisms Affected
Enteric bacteria and other eubacteria