Monobenzone [INN]
Brand names,
Monobenzone [INN]
Analogs
Monobenzone [INN]
Brand Names Mixture
Monobenzone [INN]
Chemical_Formula
C21H22N2O5S
Monobenzone [INN]
RX_link
http://www.rxlist.com/cgi/generic3/nafcillin.htm
Monobenzone [INN]
fda sheet
Monobenzone [INN]
msds (material safety sheet)
Monobenzone [INN]
Synthesis Reference
No information avaliable
Monobenzone [INN]
Molecular Weight
414.476 g/mol
Monobenzone [INN]
Melting Point
No information avaliable
Monobenzone [INN]
H2O Solubility
Soluble
Monobenzone [INN]
State
Solid
Monobenzone [INN]
LogP
3.373
Monobenzone [INN]
Dosage Forms
Powder for solution
Monobenzone [INN]
Indication
For the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drugs.
Monobenzone [INN]
Pharmacology
Nafcillin is a semisynthetic antibiotic substance derived from 6-amino-penicillanic acid. The drugs in this class are highly resistant to inactivation by staphylococcal penicillinase and are active against penicillinase-producing and non penicillinase-producing strains of Staphylococcus aureus. The penicillinase- resistant penicillins are active in vitro against a variety of other bacteria.
Monobenzone [INN]
Absorption
No information avaliable
Monobenzone [INN]
side effects and Toxicity
Serious toxicity is unlikely following large doses of nafcillin. Acute ingestion of large doses of nafcillin may cause nausea, vomiting, diarrhea and abdominal pain. Acute oliguric renal failure and hematuria may occur following large doses.
Monobenzone [INN]
Patient Information
Monobenzone [INN]
Organisms Affected
Enteric bacteria and other eubacteria