Benzyl p-hydroxyphenyl ether
Brand names,
Benzyl p-hydroxyphenyl ether
Analogs
Benzyl p-hydroxyphenyl ether
Brand Names Mixture
Benzyl p-hydroxyphenyl ether
Chemical_Formula
C21H22N2O5S
Benzyl p-hydroxyphenyl ether
RX_link
http://www.rxlist.com/cgi/generic3/nafcillin.htm
Benzyl p-hydroxyphenyl ether
fda sheet
Benzyl p-hydroxyphenyl ether
msds (material safety sheet)
Benzyl p-hydroxyphenyl ether
Synthesis Reference
No information avaliable
Benzyl p-hydroxyphenyl ether
Molecular Weight
414.476 g/mol
Benzyl p-hydroxyphenyl ether
Melting Point
No information avaliable
Benzyl p-hydroxyphenyl ether
H2O Solubility
Soluble
Benzyl p-hydroxyphenyl ether
State
Solid
Benzyl p-hydroxyphenyl ether
LogP
3.373
Benzyl p-hydroxyphenyl ether
Dosage Forms
Powder for solution
Benzyl p-hydroxyphenyl ether
Indication
For the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drugs.
Benzyl p-hydroxyphenyl ether
Pharmacology
Nafcillin is a semisynthetic antibiotic substance derived from 6-amino-penicillanic acid. The drugs in this class are highly resistant to inactivation by staphylococcal penicillinase and are active against penicillinase-producing and non penicillinase-producing strains of Staphylococcus aureus. The penicillinase- resistant penicillins are active in vitro against a variety of other bacteria.
Benzyl p-hydroxyphenyl ether
Absorption
No information avaliable
Benzyl p-hydroxyphenyl ether
side effects and Toxicity
Serious toxicity is unlikely following large doses of nafcillin. Acute ingestion of large doses of nafcillin may cause nausea, vomiting, diarrhea and abdominal pain. Acute oliguric renal failure and hematuria may occur following large doses.
Benzyl p-hydroxyphenyl ether
Patient Information
Benzyl p-hydroxyphenyl ether
Organisms Affected
Enteric bacteria and other eubacteria