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L-Captopril en es it fr

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L-Captopril Les marques, L-Captopril Analogs

L-Captopril Les marques melange

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    • L-Captopril Formule chimique

    C9H15NO3S

    L-Captopril RX lien

    http://www.rxlist.com/cgi/generic/captop.htm

    L-Captopril FDA fiche

    L-Captopril msds (fiche de securite des materiaux)

    L-Captopril MSDS

    L-Captopril Synthese de reference

    DW Cushman, le brevet américain. 4,046,889 (1977)

    L-Captopril Poids moleculaire

    217.286 g/mol

    L-Captopril Point de fusion

    106oC

    L-Captopril H2O Solubilite

    Librement soluble

    L-Captopril Etat

    Solid

    L-Captopril LogP

    0.546

    L-Captopril Formes pharmaceutiques

    Tablet (12,5 mg, 25 mg, 50 mg ou 100 mg)

    L-Captopril Indication

    Pour le traitement de l'hypertension. Il peut être utilisé seul ou en association avec des diurétiques thiazidiques.

    L-Captopril Pharmacologie

    Captopril, une enzyme de conversion (IEC), est utilisé pour traiter l'hypertension artérielle, insuffisance cardiaque congestive, et les syndromes rénaux tels que la néphropathie diabétique et la sclérodermie. L'effet indésirable et les limites pharmacocinétiques du captopril stimulé le développement des inhibiteurs de l'ECA énalapril et ultérieures.

    L-Captopril Absorption

    75% sans nourriture (la présence d'aliments dans le tractus gastro-intestinal réduit l'absorption d'environ 30 à 40 pour cent).

    L-Captopril Toxicite

    Les symptômes de surdose comprennent le coma, la léthargie, une pression artérielle basse, de la lenteur et de l'estomac et de l'irritation intestinale et l'hyperactivité.

    L-Captopril Information pour les patients

    Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

    Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

    All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

    Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

    Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

    Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

    Patients should be informed that captopril should be taken one hour before meals.

    L-Captopril Organismes affectes

    Les humains et autres mammifères