PharmacyCodes



Tensoprel en es it fr

Tensoprel Brand names, Tensoprel Analogs

Tensoprel Brand Names Mixture

  • No information avaliable

Tensoprel Chemical_Formula

C9H15NO3S

Tensoprel RX_link

http://www.rxlist.com/cgi/generic/captop.htm

Tensoprel fda sheet

Tensoprel msds (material safety sheet)

Tensoprel MSDS

Tensoprel Synthesis Reference

D. W. Cushman, U.S. Pat. 4,046,889 (1977)

Tensoprel Molecular Weight

217.286 g/mol

Tensoprel Melting Point

106oC

Tensoprel H2O Solubility

Freely soluble

Tensoprel State

Solid

Tensoprel LogP

0.546

Tensoprel Dosage Forms

Tablet (12.5 mg, 25 mg, 50 mg, or 100 mg)

Tensoprel Indication

For the treatment of hypertension. It may be used alone or in combination with thiazide diuretics.

Tensoprel Pharmacology

Captopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension, congestive heart failure, and renal syndromes such as diabetic nephropathy and scleroderma. The adverse effect and pharmacokinetic limitations of captopril stimulated the development enalapril and subsequent ACE inhibitors.

Tensoprel Absorption

75% without food (the presence of food in the gastrointestinal tract reduces absorption by about 30 to 40 percent).

Tensoprel side effects and Toxicity

Symptoms of overdose include coma, lethargy, low blood pressure, sluggishness, and stomach and intestinal irritation and hyperactivity.

Tensoprel Patient Information

Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

Patients should be informed that captopril should be taken one hour before meals.

Tensoprel Organisms Affected

Humans and other mammals