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Analogs
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Les marques melange
Alchemed NP-03 (aconite + apis mellifica + arnica montana + barberry root + calendula + cantharides + charcoal activated + echinacea angustifolia + hahnemann's causticum + hypericum perforatum + nitroglycerin + urtica urens) Alchemed NP-04 (aesculus hippocastanum + arnica montana + barium carbonate + belladonna + celandine + cinchona officinalis + nitroglycerin + oyster shells + sepia officinalis l + strophanthus hispidus) Alchemed NP-21 (belladonna + cantharides + german chamomile + nitroglycerin + phosphorus + sepia officinalis l + silver nitrate + valerian + zinc) Aribosan B31 - liq (apis mellifica + barberry root + colchicine + convallaria majalis + nitroglycerin + poison oak + potassium iodide + quinine dihyrochloride) Cactus Compositum DPS (cactus grandiflorus + nitroglycerin + potassium carbonate + spigelia) Cere Bosan B36 - liq (belladonna + hamamelis virginiana + nitroglycerin + saffron + trillium pendulum) Complex 12 (aesculus hippocastanum + apis mellifica + arnica montana + barium carbonate + barium chloride + belladonna + calcium fluoride + celandine + charcoal activated + cinchona officinalis + collinsonia canadensis + conium maculatum + echinacea angustifolia + hamamelis virginiana + lycopodium clavatum + nitroglycerin + phosphorus + ruta graveolens + sepia officinalis l + sodium chloride + strophanthus hispidus + sulfur + tobacco) Complex 15 (belladonna + cimicifuga racemosa + cinchona officinalis + glycyrrhiza glabra + nitroglycerin + oyster shells + platinum + pulsatilla + sanguinaria canadensis + sepia officinalis l + sulfur + tiger lily + vitex agnus castus) CRC-plex (arnica montana + barium chloride + calcium lactate + charcoal activated + cholesterol + convallaria majalis + epinephrine + iodine + magnesium carbonate + nitroglycerin + phosphorus + picric acid + potassium iodide + strophanthus hispidus) Ero-bosan B20-liq (nitroglycerin + pulsatilla + sanguinaria canadensis + sepia officinalis l + vitex agnus castus) From time to time (belladonna + bryonia + charcoal activated + gelsemium sempervirens + lycopodium clavatum + melilot + nitroglycerin + silicon dioxide + sodium chloride + spigelia marylandica) Globuli no 51 (barium carbonate + cactus grandiflorus + gelsemium sempervirens + nitroglycerin) Homeo-form MI - liquid (aluminum oxide + antimony trisulfide + cyclamen europaeum l. + lycopodium clavatum + melilot + nitroglycerin + silver nitrate) Homeo-form MI-tab (aluminum oxide + antimony trisulfide + cyclamen europaeum l. + lycopodium clavatum + melilot + nitroglycerin + silver nitrate) Homeodel 24 (belladonna + charcoal activated + gelsemium sempervirens + iris versicolor + lycopodium + nitroglycerin + spigelia) Homeopathic Remedy THC no.4 (aconite + arnica montana + belladonna + bryonia + cocculus indicus + gelsemium sempervirens + iris versicolor + lycopodium clavatum + nitroglycerin + potassium dichromate + pulsatilla + sanguinaria canadensis + silicon dioxide + silver nitrate + sodium chloride + spigelia marylandica + thuja occidentalis) HPB Complex DPS (barium chloride + gold + mistletoe + nitroglycerin) Ingr-bosan b34 - liq (belladonna + cimicifuga racemosa + gelsemium sempervirens + iris versicolor + nitroglycerin + spigelia anthelmia) Iper-bosan b44 - liq (baryta iodata + cactus grandiflorus + gelsemium sempervirens + nitroglycerin) L2 (apis mellifica + belladonna + juglans cinerea + nitroglycerin + phytolacca decandra + pulsatilla + spongia tosta + vitex agnus castus) L.122 - liq orl (bryonia + cactus grandiflorus + nitroglycerin + potassium carbonate) L.15 DPS (aconitinum + apocynum cannabinum + arnica montana + cactus grandiflorus + nitroglycerin) L.73 liq (belladonna + cocculus indicus + lead acetate + mugwort + nitroglycerin + periwinkle + pulsatilla + silver nitrate + valerian) Nitroglycerin in 5% dextrose inj.-100mcg/ml (dextrose + nitroglycerin) nitroglycerin in 5% dextrose inj.-200mcg/ml (dextrose + nitroglycerin) nitroglycerin in 5% dextrose inj.-400mcg/ml (dextrose + nitroglycerin) Nova - 7041 - liq (belladonna + cantharides + german chamomile + nitroglycerin + phosphorus + sepia officinalis l + silver nitrate + valerian + zinc) Nova 7025 - liq (aconite + apis mellifica + arnica montana + barberry root + calendula + cantharides + charcoal activated + echinacea angustifolia + hahnemann's causticum + hypericum perforatum + nitroglycerin + urtica urens) Nova 7028 - liq (aesculus hippocastanum + arnica montana + barium carbonate + belladonna + calcium carbonate + celandine + cinchona officinalis + nitroglycerin + sepia officinalis l + strophanthus hispidus) Nova 7037 - liq (belladonna + calcium carbonate + cinchona officinalis + nitroglycerin + platinum + pulsatilla + sanguinaria canadensis + sulfur + tiger lily + tin) Pekana - complex nr. 47 (clematis erecta + cynara scolymus + dulcamara + euphrasia officinalis + ivy + nitroglycerin + ruta graveolens + tobacco) R 47 dps (asafetida + coffee + musk + nitroglycerin + pulsatilla) R-12 dps (arnica montana + barium chloride + calcium iodide + conium maculatum + lead acetate + nitroglycerin + phosphorus + potassium iodide) R12 (arnica montana + barium chloride + calcium iodide + conium maculatum + lead acetate + nitroglycerin + phosphorus + potassium iodide) R47 (asafetida + coffee + musk + nitroglycerin + pulsatilla) THC complex #15 (belladonna + cinchona officinalis + gelsemium sempervirens + nitroglycerin + sodium chloride + sulfur) THC complex #2 (aconite + apis mellifica + arnica montana + belladonna + bryonia + cocculus indicus + ferrum phosphoricum + gelsemium sempervirens + hydrastis canadensis + iris versicolor + lycopodium clavatum + magnesium phosphate dibasic + nitroglycerin + phosphorus + potassium dichromate + potassium phosphate dibasic + pulsatilla + sanguinaria canadensis + silicon dioxide + silver nitrate + sodium chloride + spigelia marylandica + thuja occidentalis) THC complex #37 (aconite + bellis perennis + caulophyllum thalictroides + cimicifuga racemosa + nitroglycerin + pulsatilla + sanguinaria canadensis + strontium carbonate)
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Formule chimique
C3H5N3O9
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RX lien
http://www.rxlist.com/cgi/generic/ntg.htm
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FDA fiche
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msds (fiche de securite des materiaux)
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Synthese de reference
Sobrero, Ann. 64, 398 (1847)
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Poids moleculaire
227.087 g/mol
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Point de fusion
13.5oC
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H2O Solubilite
Légèrement soluble
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Etat
Liquid
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LogP
0.121
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Formes pharmaceutiques
Tablet (libération prolongée); Tablet (à libération lente); Pommade; aérosol linguale; système d'administration transdermique
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Indication
Pour la prévention de l'angine
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Pharmacologie
La nitroglycérine, un nitrate organique, est disponible sous plusieurs formes comme un vasodilatateur. La nitroglycérine est utilisée dans le Traitement de l'angine de poitrine et l'hypertension périopératoire, pour produire une hypotension contrôlée pendant les interventions chirurgicales, pour traiter les urgences hypertensives, et pour traiter l'insuffisance cardiaque congestive associée à un infarctus du myocarde.
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Absorption
Aucune information disponible
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Toxicite
Augmentation de la pression intracrânienne, avec tout ou partie des maux de tête pulsatiles persistantes, confusion, et une fièvre modérée, vertige, palpitations, troubles visuels, nausées et vomissements (éventuellement avec coliques et même de diarrhée sanglante), syncope (surtout en position debout), la faim de l'air et la dyspnée, suivis plus tard par l'effort ventilatoire réduite; diaphorèse, avec la peau soit rincée ou froide et moite; Coeur bloc et bradycardie, paralysie, coma, convulsions, mort.
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Information pour les patients
PATIENT INFORMATION
Daily headaches sometimes accompany treatment with nitroglycerin. In patients who get
these headaches, the headaches may be a marker of the activity of the drug. Patients
should resist the temptation to avoid headaches by altering the schedule of their
treatment with nitroglycerin, since loss of headache may be associated with simultaneous
loss of antianginal efficacy.
Treatment with nitroglycerin may be associated with lightheadedness on standing, especially
just after rising from a recumbent or seated position. This effect may be more frequent in
patients who have also consumed alcohol.
After normal use, there is enough residual nitroglycerin in discarded patches that they are
a potential hazard to children and pets.
A patient leaflet is supplied with the systems.
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Organismes affectes
Les humains et autres mammifères