Diladel
Categorie
Diladel Les marques, Diladel Analogs
- Acalix
- Adizem
- Altiazem
- Anginyl
- Angizem
- Anoheal
- Apo-Diltiaz
- Britiazim
- Bruzem
- Calcicard
- Cardizem
- Cardizem CD
- Cardizem SR
- Cardizen LA
- Cartia XT
- Citizem
- Cormax
- Deltazen
- Dilacor
- Dilacor-XR
- Diladel
- Dilcontin
- Dilpral
- Dilrene
- Dilt-cd
- Dilta-Hexal
- Diltia
- Dilticard
- Dilzem
- Dilzen
- Endrydil
- Herbesser
- Incoril AP
- Masdil
- Novo-Diltazem
- Nu-Diltiaz
- Syn-Diltiazem
- Tiazac Tildiem
- d-cis-Diltiazem
Diladel Les marques melange
Diladel Formule chimique
C22H26N2O4S
Diladel RX lien
http://www.rxlist.com/cgi/generic/diltiaz.htm
Diladel FDA fiche
Diladel msds (fiche de securite des materiaux)
Diladel Synthese de reference
H. Kugita et al., US. 3,562,257 (1971)
Diladel Poids moleculaire
414.519 g/mol
Diladel Point de fusion
231oC
Diladel H2O Solubilite
465 mg / L
Diladel Etat
Solid
Diladel LogP
3.141
Diladel Formes pharmaceutiques
Solution
Diladel Indication
Pour le traitement de l'hypertension
Diladel Pharmacologie
Diltiazem, un benzothiazépine inhibiteur calcique, est utilisé seul ou avec une conversion de l'angiotensine inhibiteur de l'enzyme, pour traiter l'hypertension, angine de poitrine chronique stable, et l'angine de Prinzmetal variante. Diltiazem est similaire à d'autres vasodilatateurs périphériques. Diltiazem inhibe l'influx de calcium extracellulaire à travers le myocarde et lisse vasculaire membranes des cellules musculaires éventuellement par déformation de la canal, l'inhibition des mécanismes de déclenchement d'ions de contrôle, et / ou interférer avec la libération de calcium par le réticulum sarcoplasmique. La diminution du calcium intracellulaire inhibe les processus contractiles des cellules du muscle lisse du myocarde, la dilatation provoque des artères coronaires et systémiques, l'augmentation de l'apport d'oxygène vers les tissus du myocarde, une diminution de la résistance périphérique totale, une diminution systémique la pression artérielle, et une diminution de la postcharge.
Diladel Absorption
Diltiazem est bien absorbé par le tractus gastro-intestinal, mais subit substantielle de premier passage hépatique effet.
Diladel Toxicite
DL50 = 740mg/kg (par voie orale chez la souris)
Diladel Information pour les patients
PATIENT INFORMATION
Take this medicine exactly as directed even if you feel well and do not notice any signs of chest pain.
Do not take more of this medicine and do not take it more often than your doctor ordered.
Do not miss any doses.
Diltiazem is a calcium channel blocking agents. For the calcium channel blocking agents, the following should be considered:
-Tell your doctor if you have ever had any unusual or allergic reaction to amlodipine, bepridil, diltiazem, felodipine, flunarizine, isradipine, nicardipine, nifedipine, nimodipine, or verapamil. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
-Calcium channel blocking agents have not been studied in pregnant women. However, studies in animals have shown that large doses of calcium channel blocking agents cause birth defects, prolonged pregnancy, poor bone development in the offspring, and stillbirth.
-Although bepridil, diltiazem, nifedipine, verapamil, and possibly other calcium channel blocking agents, pass into breast milk, they have not been reported to cause problems in nursing babies.
-Although there is no specific information comparing use of this medicine in children with use in other age groups, it is not expected to cause different side effects or problems in children than it does in adults.
-Elderly people may be especially sensitive to the effects of calcium channel blocking agents. This may increase the chance of side effects during treatment. A lower starting dose may be required.
-The presence of other medical problems may affect the use of the calcium channel blocking agents. Make sure you tell your doctor if you have any other medical problems, especially
Follow Rxlist link and drugs.com link and other links for detailed information.
Take this medicine exactly as directed even if you feel well and do not notice any signs of chest pain.
Do not take more of this medicine and do not take it more often than your doctor ordered.
Do not miss any doses.
Diltiazem is a calcium channel blocking agents. For the calcium channel blocking agents, the following should be considered:
-Tell your doctor if you have ever had any unusual or allergic reaction to amlodipine, bepridil, diltiazem, felodipine, flunarizine, isradipine, nicardipine, nifedipine, nimodipine, or verapamil. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
-Calcium channel blocking agents have not been studied in pregnant women. However, studies in animals have shown that large doses of calcium channel blocking agents cause birth defects, prolonged pregnancy, poor bone development in the offspring, and stillbirth.
-Although bepridil, diltiazem, nifedipine, verapamil, and possibly other calcium channel blocking agents, pass into breast milk, they have not been reported to cause problems in nursing babies.
-Although there is no specific information comparing use of this medicine in children with use in other age groups, it is not expected to cause different side effects or problems in children than it does in adults.
-Elderly people may be especially sensitive to the effects of calcium channel blocking agents. This may increase the chance of side effects during treatment. A lower starting dose may be required.
-The presence of other medical problems may affect the use of the calcium channel blocking agents. Make sure you tell your doctor if you have any other medical problems, especially
Follow Rxlist link and drugs.com link and other links for detailed information.
Diladel Organismes affectes
Les humains et autres mammifères
