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Dilabar Marca los nombres de mezcla

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    • Dilabar Formula quimica

    C9H15NO3S

    Dilabar RX enlace

    http://www.rxlist.com/cgi/generic/captop.htm

    Dilabar FDA hoja

    Dilabar MSDS (hoja de seguridad de materiales)

    Dilabar MSDS

    Dilabar Sintesis de referencia

    DW Cushman, EE.UU. Pat. 4,046,889 (1977)

    Dilabar Peso molecular

    217.286 g/mol

    Dilabar Punto de fusion

    106oC

    Dilabar H2O Solubilidad

    Muy soluble

    Dilabar Estado

    Solid

    Dilabar LogP

    0.546

    Dilabar Formas de dosificacion

    Tablet (12,5 mg, 25 mg, 50 mg o 100 mg)

    Dilabar Indicacion

    Para el tratamiento de la hipertensión. Se puede utilizar solo o en combinación con diuréticos tiazídicos.

    Dilabar Farmacologia

    Captopril, un inhibidor de la enzima convertidora de angiotensina (ECA), se utiliza para tratar la hipertensión, insuficiencia cardiaca congestiva, y síndromes renales como la nefropatía diabética y la esclerodermia. El efecto adverso y las limitaciones farmacocinéticas del captopril estimulado el desarrollo de inhibidores de la ECA enalapril y posteriores.

    Dilabar Absorcion

    75% sin alimentos (la presencia de alimentos en el tracto gastrointestinal reduce la absorción de unos 30 a 40 por ciento).

    Dilabar Toxicidad

    Los síntomas de sobredosis incluyen coma, letargo, baja presión arterial, la lentitud, y el estómago e irritación intestinal y la hiperactividad.

    Dilabar Informacion de Pacientes

    Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

    Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

    All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

    Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

    Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

    Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

    Patients should be informed that captopril should be taken one hour before meals.

    Dilabar Organismos afectados

    Humanos y otros mamíferos