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Apopril en es it fr

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Apopril Nombres de marca, Apopril Analogos

Apopril Marca los nombres de mezcla

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    • Apopril Formula quimica

    C9H15NO3S

    Apopril RX enlace

    http://www.rxlist.com/cgi/generic/captop.htm

    Apopril FDA hoja

    Apopril MSDS (hoja de seguridad de materiales)

    Apopril MSDS

    Apopril Sintesis de referencia

    DW Cushman, EE.UU. Pat. 4,046,889 (1977)

    Apopril Peso molecular

    217.286 g/mol

    Apopril Punto de fusion

    106oC

    Apopril H2O Solubilidad

    Muy soluble

    Apopril Estado

    Solid

    Apopril LogP

    0.546

    Apopril Formas de dosificacion

    Tablet (12,5 mg, 25 mg, 50 mg o 100 mg)

    Apopril Indicacion

    Para el tratamiento de la hipertensión. Se puede utilizar solo o en combinación con diuréticos tiazídicos.

    Apopril Farmacologia

    Captopril, un inhibidor de la enzima convertidora de angiotensina (ECA), se utiliza para tratar la hipertensión, insuficiencia cardiaca congestiva, y síndromes renales como la nefropatía diabética y la esclerodermia. El efecto adverso y las limitaciones farmacocinéticas del captopril estimulado el desarrollo de inhibidores de la ECA enalapril y posteriores.

    Apopril Absorcion

    75% sin alimentos (la presencia de alimentos en el tracto gastrointestinal reduce la absorción de unos 30 a 40 por ciento).

    Apopril Toxicidad

    Los síntomas de sobredosis incluyen coma, letargo, baja presión arterial, la lentitud, y el estómago e irritación intestinal y la hiperactividad.

    Apopril Informacion de Pacientes

    Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

    Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

    All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

    Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

    Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

    Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

    Patients should be informed that captopril should be taken one hour before meals.

    Apopril Organismos afectados

    Humanos y otros mamíferos