Acepril

• Angiotensin-Converting Enzyme Inhibitors
• Antihypertensive Agents
• ATC:C09AA01

• Acediur
• Aceplus
• Acepress
• Acepril
• Alopresin
• Apopril
• Capoten
• Capozide
• Captolane
• Captopril [Usan:Ban:Inn:Jan]
• Captoprilum [Inn-Latin]
• Captopryl
• Captoril
• Cesplon
• Dilabar
• Garranil
• Hipertil
• Hypertil
• L-Captopril
• Lopirin
• Lopirin [Switzerland]
• Lopril
• Tenosbon
• Tensobon
• Tensoprel

No information avaliable

C₉H₁₅NO₃S

http://www.rxlist.com/cgi/generic/captop.htm

Acepril MSDS

DW Cushman, EE.UU. Pat. 4,046,889 (1977)

217.286 g/mol

106^oC

Muy soluble

Solid

0.546

Tablet (12,5 mg, 25 mg, 50 mg o 100 mg)

Para el tratamiento de la hipertensión. Se puede utilizar solo o en combinación con diuréticos tiazídicos.

Captopril, un inhibidor de la enzima convertidora de angiotensina (ECA), se utiliza para tratar la hipertensión, insuficiencia cardiaca congestiva, y síndromes renales como la nefropatía diabética y la esclerodermia. El efecto adverso y las limitaciones farmacocinéticas del captopril estimulado el desarrollo de inhibidores de la ECA enalapril y posteriores.

75% sin alimentos (la presencia de alimentos en el tracto gastrointestinal reduce la absorción de unos 30 a 40 por ciento).

Los síntomas de sobredosis incluyen coma, letargo, baja presión arterial, la lentitud, y el estómago e irritación intestinal y la hiperactividad.

Patients should be advised to immediately report to their physician any signs or symptoms suggesting angioedema (e.g., swelling of face, eyes, lips, tongue, larynx and extremities; difficulty in swallowing or breathing; hoarseness) and to discontinue therapy.

Patients should be told to report promptly any indication of infection (e.g., sore throat, fever),which may be a sign of neutropenia, or of progressive edema which might be related to proteinuria and nephrotic syndrome.

All patients should be cautioned that excessive perspiration and dehydration may lead to an excessive fall in blood pressure because of reduction in fluid volume. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with the physician.

Patients should be advised not to use potassium-sparing diuret-ics, potassium supplements or potassium-containing salt substitutes without consulting their physician.

Patients should be warned against interruption or discontinuation of medication unless instructed by the physician.

Heart failure patients on captopril therapy should be cautioned against rapid increases in physical activity.

Patients should be informed that captopril should be taken one hour before meals.

Humanos y otros mamíferos