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VDN Brand names, VDN Analogs

VDN Brand Names Mixture

  • No information avaliable

VDN Chemical_Formula


VDN RX_link


VDN fda sheet


VDN msds (material safety sheet)

VDN Synthesis Reference

No information avaliable

VDN Molecular Weight

488.604 g/mol

VDN Melting Point

192 oC

VDN H2O Solubility

0.11 mg/mL (HCl salt)

VDN State



No information avaliable

VDN Dosage Forms

Tablet (5, 10, and 20 mg)

VDN Indication

Used for the treatment of erectile dysfunction

VDN Pharmacology

Vardenafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Vardenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. This means that, with vardenafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, vardenafil should not cause an erection.

VDN Absorption

Vardenafil is rapidly absorbed with absolute bioavailability of approximately 15%.

VDN side effects and Toxicity

Symptoms of overdose include vision changes and back and muscle pain.

VDN Patient Information

VDN Organisms Affected

Humans and other mammals