Ultane
Brand names,
Ultane
Analogs
Ultane
Brand Names Mixture
Ultane
Chemical_Formula
C4H3F7O
Ultane
RX_link
http://www.rxlist.com/cgi/generic2/sevoflurane.htm
Ultane
fda sheet
Ultane
msds (material safety sheet)
Ultane
Synthesis Reference
No information avaliable
Ultane
Molecular Weight
200.055 g/mol
Ultane
Melting Point
< 25°C (boiling point: 58.6°C)
Ultane
H2O Solubility
Very slightly soluble
Ultane
State
Liquid
Ultane
LogP
2.212
Ultane
Dosage Forms
Liquid (in a canister, to be vaporized for inhalation)
Ultane
Indication
Used for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.
Ultane
Pharmacology
Sevoflurane (also called fluoromethyl) is a halogenated ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. It is often administered in nitrous oxide and pure oxygen. After desflurane it is the volatile anesthetic with the fastest onset and offset. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Ultane
Absorption
Rapidly absorbed into circulation via the lungs, however solubility in the blood is low.
Ultane
side effects and Toxicity
LC50=49881 ppm/hr (rat), LD50=10.8 g/kg (rat)
Ultane
Patient Information
No information avaliable
Ultane
Organisms Affected
Humans and other mammals