Sevorane

Sevorane Brand names, Sevorane Analogs

Sevorane Brand Names Mixture

No information avaliable

Sevorane Chemical_Formula

C₄H₃F₇O

Sevorane RX_link

http://www.rxlist.com/cgi/generic2/sevoflurane.htm

Sevorane fda sheet

Sevorane FDA

Sevorane msds (material safety sheet)

Sevorane MSDS

Sevorane Synthesis Reference

No information avaliable

Sevorane Molecular Weight

200.055 g/mol

Sevorane Melting Point

< 25°C (boiling point: 58.6°C)

Sevorane H₂O Solubility

Very slightly soluble

Sevorane State

Liquid

Sevorane LogP

2.212

Sevorane Dosage Forms

Liquid (in a canister, to be vaporized for inhalation)

Sevorane Indication

Used for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.

Sevorane Pharmacology

Sevoflurane (also called fluoromethyl) is a halogenated ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. It is often administered in nitrous oxide and pure oxygen. After desflurane it is the volatile anesthetic with the fastest onset and offset. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.

Sevorane Absorption

Rapidly absorbed into circulation via the lungs, however solubility in the blood is low.

Sevorane side effects and Toxicity

LC50=49881 ppm/hr (rat), LD₅₀=10.8 g/kg (rat)

Sevorane Patient Information