Teslak
Teslak Brand names, Teslak Analogs
Teslak Brand Names Mixture
- No information avaliable
Teslak Chemical_Formula
C19H24O3
Teslak RX_link
http://www.rxlist.com/cgi/generic2/testolactone.htm
Teslak fda sheet
Teslak msds (material safety sheet)
Teslak Synthesis Reference
No information avaliable
Teslak Molecular Weight
300.392 g/mol
Teslak Melting Point
218.5 oC
Teslak H2O Solubility
Slightly soluble (27.4 mg/L)
Teslak State
Solid
Teslak LogP
3.663
Teslak Dosage Forms
For oral administration as tablets providing 50 mg testolactone per tablet
Teslak Indication
For palliative treatment of advanced breast cancer in postmenopausal women.
Teslak Pharmacology
Testolactone is a synthetic anti-neoplastic agent that is structurally distinct from the androgen steroid nucleus in possessing a six-membered lactone ring in place of the usual five-membered carbocyclic D-ring. Despite some similarity to testosterone, testolactone has no in vivo androgenic effect. No other hormonal effects have been reported in clinical studies in patients receiving testolactone.
Teslak Absorption
Testolactone is well absorbed from the gastrointestinal tract.
Teslak side effects and Toxicity
Oral LD50s in mouse and dog are 1630 mg/kg and 593-926 mg/kg, respectively.
Teslak Patient Information
Teslak Organisms Affected
Humans and other mammals
