Teolit
Teolit Brand names, Teolit Analogs
Teolit Brand Names Mixture
- No information avaliable
Teolit Chemical_Formula
C19H24O3
Teolit RX_link
http://www.rxlist.com/cgi/generic2/testolactone.htm
Teolit fda sheet
Teolit msds (material safety sheet)
Teolit Synthesis Reference
No information avaliable
Teolit Molecular Weight
300.392 g/mol
Teolit Melting Point
218.5 oC
Teolit H2O Solubility
Slightly soluble (27.4 mg/L)
Teolit State
Solid
Teolit LogP
3.663
Teolit Dosage Forms
For oral administration as tablets providing 50 mg testolactone per tablet
Teolit Indication
For palliative treatment of advanced breast cancer in postmenopausal women.
Teolit Pharmacology
Testolactone is a synthetic anti-neoplastic agent that is structurally distinct from the androgen steroid nucleus in possessing a six-membered lactone ring in place of the usual five-membered carbocyclic D-ring. Despite some similarity to testosterone, testolactone has no in vivo androgenic effect. No other hormonal effects have been reported in clinical studies in patients receiving testolactone.
Teolit Absorption
Testolactone is well absorbed from the gastrointestinal tract.
Teolit side effects and Toxicity
Oral LD50s in mouse and dog are 1630 mg/kg and 593-926 mg/kg, respectively.
Teolit Patient Information
Teolit Organisms Affected
Humans and other mammals
