Teslac
Teslac Brand names, Teslac Analogs
Teslac Brand Names Mixture
- No information avaliable
Teslac Chemical_Formula
C19H24O3
Teslac RX_link
http://www.rxlist.com/cgi/generic2/testolactone.htm
Teslac fda sheet
Teslac msds (material safety sheet)
Teslac Synthesis Reference
No information avaliable
Teslac Molecular Weight
300.392 g/mol
Teslac Melting Point
218.5 oC
Teslac H2O Solubility
Slightly soluble (27.4 mg/L)
Teslac State
Solid
Teslac LogP
3.663
Teslac Dosage Forms
For oral administration as tablets providing 50 mg testolactone per tablet
Teslac Indication
For palliative treatment of advanced breast cancer in postmenopausal women.
Teslac Pharmacology
Testolactone is a synthetic anti-neoplastic agent that is structurally distinct from the androgen steroid nucleus in possessing a six-membered lactone ring in place of the usual five-membered carbocyclic D-ring. Despite some similarity to testosterone, testolactone has no in vivo androgenic effect. No other hormonal effects have been reported in clinical studies in patients receiving testolactone.
Teslac Absorption
Testolactone is well absorbed from the gastrointestinal tract.
Teslac side effects and Toxicity
Oral LD50s in mouse and dog are 1630 mg/kg and 593-926 mg/kg, respectively.
Teslac Patient Information
Teslac Organisms Affected
Humans and other mammals
