Teniposide
Teniposide Brand names, Teniposide Analogs
Teniposide Brand Names Mixture
- No information avaliable
Teniposide Chemical_Formula
C32H32O13S
Teniposide RX_link
http://www.rxlist.com/cgi/generic2/teniposide.htm
Teniposide fda sheet
Teniposide msds (material safety sheet)
Teniposide Synthesis Reference
No information avaliable
Teniposide Molecular Weight
656.655 g/mol
Teniposide Melting Point
No information avaliable
Teniposide H2O Solubility
No information avaliable
Teniposide State
Solid
Teniposide LogP
1.963
Teniposide Dosage Forms
Liquid
Teniposide Indication
Treatment of refractory acute lymphoblastic leukaemia
Teniposide Pharmacology
Teniposide is a phase-specific cytotoxic drug, acting in the late S or early G 2 phase of the cell cycle, thus preventing cells from entering mitosis. Teniposide causes dose-dependent single- and double-stranded breaks in DNA and DNA: protein cross-links. The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide does not intercalate into DNA or bind strongly to DNA.
Teniposide Absorption
No information avaliable
Teniposide side effects and Toxicity
No information avaliable
Teniposide Patient Information
No information avaliable
Teniposide Organisms Affected
Humans and other mammals
