Veham-Sandoz
Brand names,
Veham-Sandoz
Analogs
Veham-Sandoz
Brand Names Mixture
Veham-Sandoz
Chemical_Formula
C32H32O13S
Veham-Sandoz
RX_link
http://www.rxlist.com/cgi/generic2/teniposide.htm
Veham-Sandoz
fda sheet
Veham-Sandoz
msds (material safety sheet)
Veham-Sandoz
Synthesis Reference
No information avaliable
Veham-Sandoz
Molecular Weight
656.655 g/mol
Veham-Sandoz
Melting Point
No information avaliable
Veham-Sandoz
H2O Solubility
No information avaliable
Veham-Sandoz
State
Solid
Veham-Sandoz
LogP
1.963
Veham-Sandoz
Dosage Forms
Liquid
Veham-Sandoz
Indication
Treatment of refractory acute lymphoblastic leukaemia
Veham-Sandoz
Pharmacology
Teniposide is a phase-specific cytotoxic drug, acting in the late S or early G 2 phase of the cell cycle, thus preventing cells from entering mitosis. Teniposide causes dose-dependent single- and double-stranded breaks in DNA and DNA: protein cross-links. The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide does not intercalate into DNA or bind strongly to DNA.
Veham-Sandoz
Absorption
No information avaliable
Veham-Sandoz
side effects and Toxicity
No information avaliable
Veham-Sandoz
Patient Information
No information avaliable
Veham-Sandoz
Organisms Affected
Humans and other mammals