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PTG Brand names, PTG Analogs

PTG Brand Names Mixture

  • No information avaliable

PTG Chemical_Formula

C32H32O13S

PTG RX_link

http://www.rxlist.com/cgi/generic2/teniposide.htm

PTG fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=110

PTG msds (material safety sheet)

PTG Synthesis Reference

No information avaliable

PTG Molecular Weight

656.655 g/mol

PTG Melting Point

No information avaliable

PTG H2O Solubility

No information avaliable

PTG State

Solid

PTG LogP

1.963

PTG Dosage Forms

Liquid

PTG Indication

Treatment of refractory acute lymphoblastic leukaemia

PTG Pharmacology

Teniposide is a phase-specific cytotoxic drug, acting in the late S or early G 2 phase of the cell cycle, thus preventing cells from entering mitosis. Teniposide causes dose-dependent single- and double-stranded breaks in DNA and DNA: protein cross-links. The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide does not intercalate into DNA or bind strongly to DNA.

PTG Absorption

No information avaliable

PTG side effects and Toxicity

No information avaliable

PTG Patient Information

No information avaliable

PTG Organisms Affected

Humans and other mammals