PTG
PTG Brand names, PTG Analogs
PTG Brand Names Mixture
- No information avaliable
PTG Chemical_Formula
C32H32O13S
PTG RX_link
http://www.rxlist.com/cgi/generic2/teniposide.htm
PTG fda sheet
PTG msds (material safety sheet)
PTG Synthesis Reference
No information avaliable
PTG Molecular Weight
656.655 g/mol
PTG Melting Point
No information avaliable
PTG H2O Solubility
No information avaliable
PTG State
Solid
PTG LogP
1.963
PTG Dosage Forms
Liquid
PTG Indication
Treatment of refractory acute lymphoblastic leukaemia
PTG Pharmacology
Teniposide is a phase-specific cytotoxic drug, acting in the late S or early G 2 phase of the cell cycle, thus preventing cells from entering mitosis. Teniposide causes dose-dependent single- and double-stranded breaks in DNA and DNA: protein cross-links. The mechanism of action appears to be related to the inhibition of type II topoisomerase activity since teniposide does not intercalate into DNA or bind strongly to DNA.
PTG Absorption
No information avaliable
PTG side effects and Toxicity
No information avaliable
PTG Patient Information
No information avaliable
PTG Organisms Affected
Humans and other mammals
