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Tenex Brand names, Tenex Analogs

Tenex Brand Names Mixture

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Tenex Chemical_Formula


Tenex RX_link


Tenex fda sheet

Tenex msds (material safety sheet)

Tenex Synthesis Reference

J. B. Bream, C.W. Coward et al.; U.S. Pat. 3,632,645 (1972)

Tenex Molecular Weight

246.093 g/mol

Tenex Melting Point

225-227 oC

Tenex H2O Solubility

1892 mg/L

Tenex State


Tenex LogP


Tenex Dosage Forms

Tablet (oral)

Tenex Indication

For use in the management of hypertension.

Tenex Pharmacology

Similar to clonidine, guanfacine is a centrally-acting, alpha(2)-adrenergic receptor agonist used alone or in combination with other drugs for the treatment of hypertension.

Tenex Absorption

Rapid and complete, with an oral bioavailability of approximately 80%.

Tenex side effects and Toxicity

Symptoms of overdose include drowsiness, lethargy, bradycardia and hypotension. LD50=165mg/kg (orally in mice)

Tenex Patient Information

Patients who receive guanfacine should be advised to exercise caution when operating dangerous machinery or driving motor vehicles until it is determined that they do not become drowsy or dizzy from the medication. Patients should be warned that their tolerance for alcohol and other CNS depressants may be diminished. Patients should be advised not to discontinue therapy abruptly.

Tenex Organisms Affected

Humans and other mammals