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Estulic Brand names, Estulic Analogs

Estulic Brand Names Mixture

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Estulic Chemical_Formula


Estulic RX_link

Estulic fda sheet

Estulic msds (material safety sheet)

Estulic Synthesis Reference

J. B. Bream, C.W. Coward et al.; U.S. Pat. 3,632,645 (1972)

Estulic Molecular Weight

246.093 g/mol

Estulic Melting Point

225-227 oC

Estulic H2O Solubility

1892 mg/L

Estulic State


Estulic LogP


Estulic Dosage Forms

Tablet (oral)

Estulic Indication

For use in the management of hypertension.

Estulic Pharmacology

Similar to clonidine, guanfacine is a centrally-acting, alpha(2)-adrenergic receptor agonist used alone or in combination with other drugs for the treatment of hypertension.

Estulic Absorption

Rapid and complete, with an oral bioavailability of approximately 80%.

Estulic side effects and Toxicity

Symptoms of overdose include drowsiness, lethargy, bradycardia and hypotension. LD50=165mg/kg (orally in mice)

Estulic Patient Information

Patients who receive guanfacine should be advised to exercise caution when operating dangerous machinery or driving motor vehicles until it is determined that they do not become drowsy or dizzy from the medication. Patients should be warned that their tolerance for alcohol and other CNS depressants may be diminished. Patients should be advised not to discontinue therapy abruptly.

Estulic Organisms Affected

Humans and other mammals