Splendil Er
Splendil Er Brand names, Splendil Er Analogs
Splendil Er Brand Names Mixture
- No information avaliable
Splendil Er Chemical_Formula
C12H21N5O2S2
Splendil Er RX_link
http://www.rxlist.com/cgi/generic/nizat.htm
Splendil Er fda sheet
Splendil Er msds (material safety sheet)
Splendil Er Synthesis Reference
R. P. Pioch, U.S. Pat. 4,375,547 (1982)
Splendil Er Molecular Weight
331.46 g/mol
Splendil Er Melting Point
203 oC
Splendil Er H2O Solubility
10-33mg/mL
Splendil Er State
Solid
Splendil Er LogP
1.506
Splendil Er Dosage Forms
Capsule (150, 300 mg)
Splendil Er Indication
For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.
Splendil Er Pharmacology
Nizatidine is a competitive, reversible inhibitor of histamine at the histamine H2-receptors, particularly those in the gastric parietal cells. By inhibiting the action of histamine on stomach cells, nizatidine reduces stomach acid production. Nizatidine had no demonstrable antiandrogenic action. Full-dose therapy for the problems treated by nizatidine lasts no longer than 8 weeks. It has been demonstrated that treatment with a reduced dose of nizatidine is effective as maintenance therapy following healing of active duodenal ulcers.
Splendil Er Absorption
Rapid (bioavailability of nizatidine exceeds 70%)
Splendil Er side effects and Toxicity
Oral, rat LD50: 301 mg/kg. Symptoms of overdose include cholinergic-type effects including lacrimation, salivation, emesis, miosis, and diarrhea.
Splendil Er Patient Information
Splendil Er Organisms Affected
Humans and other mammals
