Nizax

Nizax Brand names, Nizax Analogs

Nizax Brand Names Mixture

No information avaliable

Nizax Chemical_Formula

C₁₂H₂₁N₅O₂S₂

Nizax RX_link

http://www.rxlist.com/cgi/generic/nizat.htm

Nizax fda sheet

Nizax FDA

Nizax msds (material safety sheet)

Nizax Synthesis Reference

R. P. Pioch, U.S. Pat. 4,375,547 (1982)

Nizax Molecular Weight

331.46 g/mol

Nizax Melting Point

203 ^oC

Nizax H₂O Solubility

10-33mg/mL

Nizax State

Solid

Nizax LogP

1.506

Nizax Dosage Forms

Capsule (150, 300 mg)

Nizax Indication

For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.

Nizax Pharmacology

Nizatidine is a competitive, reversible inhibitor of histamine at the histamine H2-receptors, particularly those in the gastric parietal cells. By inhibiting the action of histamine on stomach cells, nizatidine reduces stomach acid production. Nizatidine had no demonstrable antiandrogenic action. Full-dose therapy for the problems treated by nizatidine lasts no longer than 8 weeks. It has been demonstrated that treatment with a reduced dose of nizatidine is effective as maintenance therapy following healing of active duodenal ulcers.

Nizax Absorption

Rapid (bioavailability of nizatidine exceeds 70%)

Nizax side effects and Toxicity

Oral, rat LD₅₀: 301 mg/kg. Symptoms of overdose include cholinergic-type effects including lacrimation, salivation, emesis, miosis, and diarrhea.

Nizax Patient Information

Nizax Organisms Affected

Humans and other mammals