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Axid Brand names, Axid Analogs

Axid Brand Names Mixture

  • No information avaliable

Axid Chemical_Formula

C12H21N5O2S2

Axid RX_link

http://www.rxlist.com/cgi/generic/nizat.htm

Axid fda sheet

Axid FDA

Axid msds (material safety sheet)

Axid Synthesis Reference

R. P. Pioch, U.S. Pat. 4,375,547 (1982)

Axid Molecular Weight

331.46 g/mol

Axid Melting Point

203 oC

Axid H2O Solubility

10-33mg/mL

Axid State

Solid

Axid LogP

1.506

Axid Dosage Forms

Capsule (150, 300 mg)

Axid Indication

For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.

Axid Pharmacology

Nizatidine is a competitive, reversible inhibitor of histamine at the histamine H2-receptors, particularly those in the gastric parietal cells. By inhibiting the action of histamine on stomach cells, nizatidine reduces stomach acid production. Nizatidine had no demonstrable antiandrogenic action. Full-dose therapy for the problems treated by nizatidine lasts no longer than 8 weeks. It has been demonstrated that treatment with a reduced dose of nizatidine is effective as maintenance therapy following healing of active duodenal ulcers.

Axid Absorption

Rapid (bioavailability of nizatidine exceeds 70%)

Axid side effects and Toxicity

Oral, rat LD50: 301 mg/kg. Symptoms of overdose include cholinergic-type effects including lacrimation, salivation, emesis, miosis, and diarrhea.

Axid Patient Information

Axid Organisms Affected

Humans and other mammals