Rythmol SR en es it fr

Rythmol SR Brand names, Rythmol SR Analogs

Rythmol SR Brand Names Mixture

  • No information avaliable

Rythmol SR Chemical_Formula


Rythmol SR RX_link


Rythmol SR fda sheet

Rythmol_SR FDA

Rythmol SR msds (material safety sheet)

Rythmol_SR MSDS

Rythmol SR Synthesis Reference

No information avaliable

Rythmol SR Molecular Weight

341.444 g/mol

Rythmol SR Melting Point

No information avaliable

Rythmol SR H2O Solubility

Slightly soluble

Rythmol SR State


Rythmol SR LogP


Rythmol SR Dosage Forms

Tablet (150, 225 and 300 mg)

Rythmol SR Indication

Used to prolong the time to recurrence of paroxysmal atrial fibrillation/flutter (PAF) associated with disabling symptoms in patients without structural heart disease. Also used for the treatment of life-threatening documented ventricular arrhythmias, such as sustained ventricular tachycardia.

Rythmol SR Pharmacology

Propafenone is a Class 1C antiarrhythmic drug with local anesthetic effects, and a direct stabilizing action on myocardial membranes. It is used in the treatment of atrial and ventricular arrhythmias. It works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitablity of the cells. Propafenone has local anesthetic activity approximately equal to procaine.

Rythmol SR Absorption

Nearly completely absorbed following oral administration (90%). Systemic bioavailability ranges from 5 to 50%, due to significant first-pass metabolism. This wide range in systemic bioavailability is related to two factors: presence of food (food increases bioavailability) and dosage (bioavailability is 3.4% for a 150-mg tablet compared to 10.6% for a 300-mg tablet).

Rythmol SR side effects and Toxicity

Symptoms of propafenone overdose (usually most severe within the first 3 hours) may include convulsions (rarely), heartbeat irregularities, low blood pressure, and sleepiness.

Rythmol SR Patient Information

No information avaliable

Rythmol SR Organisms Affected

Humans and other mammals