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Rythmol Brand names, Rythmol Analogs

Rythmol Brand Names Mixture

  • No information avaliable

Rythmol Chemical_Formula


Rythmol RX_link


Rythmol fda sheet

Rythmol FDA

Rythmol msds (material safety sheet)

Rythmol MSDS

Rythmol Synthesis Reference

No information avaliable

Rythmol Molecular Weight

341.444 g/mol

Rythmol Melting Point

No information avaliable

Rythmol H2O Solubility

Slightly soluble

Rythmol State


Rythmol LogP


Rythmol Dosage Forms

Tablet (150, 225 and 300 mg)

Rythmol Indication

Used to prolong the time to recurrence of paroxysmal atrial fibrillation/flutter (PAF) associated with disabling symptoms in patients without structural heart disease. Also used for the treatment of life-threatening documented ventricular arrhythmias, such as sustained ventricular tachycardia.

Rythmol Pharmacology

Propafenone is a Class 1C antiarrhythmic drug with local anesthetic effects, and a direct stabilizing action on myocardial membranes. It is used in the treatment of atrial and ventricular arrhythmias. It works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitablity of the cells. Propafenone has local anesthetic activity approximately equal to procaine.

Rythmol Absorption

Nearly completely absorbed following oral administration (90%). Systemic bioavailability ranges from 5 to 50%, due to significant first-pass metabolism. This wide range in systemic bioavailability is related to two factors: presence of food (food increases bioavailability) and dosage (bioavailability is 3.4% for a 150-mg tablet compared to 10.6% for a 300-mg tablet).

Rythmol side effects and Toxicity

Symptoms of propafenone overdose (usually most severe within the first 3 hours) may include convulsions (rarely), heartbeat irregularities, low blood pressure, and sleepiness.

Rythmol Patient Information

No information avaliable

Rythmol Organisms Affected

Humans and other mammals