Roxicam
Brand names,
Roxicam
Analogs
Roxicam
Brand Names Mixture
- Skin Shield Liquid Bandage (Alcohol Anhydrous + Benzethonium Chloride + Dyclonine Hydrochloride)
- Tanac Medicated Gel (Allantoin + Dyclonine Hydrochloride)
Roxicam
Chemical_Formula
C27H36O8
Roxicam
RX_link
http://www.rxlist.com/cgi/generic2/prednicarbate.htm
Roxicam
fda sheet
Roxicam
msds (material safety sheet)
Roxicam
Synthesis Reference
No information avaliable
Roxicam
Molecular Weight
488.57 g/mol
Roxicam
Melting Point
No information avaliable
Roxicam
H2O Solubility
No information avaliable
Roxicam
State
No information avaliable
Roxicam
LogP
3.392
Roxicam
Dosage Forms
Cream; Ointment
Roxicam
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Roxicam
Pharmacology
Corticosteroids diffuse across cell membranes and complex with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of messenger RNA (mRNA) and subsequent protein synthesis of various inhibitory enzymes responsible for the anti-inflammatory effects of topical corticosteroids. These anti-inflammatory effects include inhibition of early processes such as edema, fibrin deposition, capillary dilatation, movement of phagocytes into the area, and phagocytic activities. Later processes, such as capillary production, collagen deposition, and keloid formation also are inhibited by corticosteroids.
Roxicam
Absorption
Absorbed systemically across the stratum corneum.
Roxicam
side effects and Toxicity
No information avaliable
Roxicam
Patient Information
No information avaliable
Roxicam
Organisms Affected
Humans and other mammals