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Brand names,
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Analogs
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Brand Names Mixture
- Skin Shield Liquid Bandage (Alcohol Anhydrous + Benzethonium Chloride + Dyclonine Hydrochloride)
- Tanac Medicated Gel (Allantoin + Dyclonine Hydrochloride)
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Chemical_Formula
C27H36O8
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RX_link
http://www.rxlist.com/cgi/generic2/prednicarbate.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
488.57 g/mol
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Melting Point
No information avaliable
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H2O Solubility
No information avaliable
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State
No information avaliable
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LogP
3.392
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Dosage Forms
Cream; Ointment
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Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
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Pharmacology
Corticosteroids diffuse across cell membranes and complex with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of messenger RNA (mRNA) and subsequent protein synthesis of various inhibitory enzymes responsible for the anti-inflammatory effects of topical corticosteroids. These anti-inflammatory effects include inhibition of early processes such as edema, fibrin deposition, capillary dilatation, movement of phagocytes into the area, and phagocytic activities. Later processes, such as capillary production, collagen deposition, and keloid formation also are inhibited by corticosteroids.
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Absorption
Absorbed systemically across the stratum corneum.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals